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Centrifuge Calibration Service in San Diego

At Biotechnical Services, Inc., we ensure quality control of your GLP and GMP settings by providing you with the premier centrifuge calibration in San Diego. Without proper calibration of centrifuge time, speed, sample, and process quality will be adversely affected. When a centrifuge underperforms, it may lead to improper separation of sample components or soft pellets, resulting in low-quality samples and carrying over of contaminants.

However, when your centrifuge works faster than normal, it may contaminate the samples with host protein and DNA by inducing cell lysis. Speed accuracy is vital in clinical sample preparation. Less than optimal centrifugation of serum and plasma can cause sample failure, leading to more retesting and further investigation of the samples, which is time-consuming, expensive, and leads to inefficient laboratory operations.

At Biotechnical Services, Inc., we save you time and money by making your centrifuges work at optimal conditions with accurate temperatures and speeds while completing the assigned tasks on time. Our experienced technicians can precisely optimize all centrifuge calibration parameters, i.e., time, speed, and temperature. We have the confidence to provide you with the best centrifuge calibration in San Diego and its surrounding areas.

How To Calibrate Your Centrifuge


Before starting the calibration process, ensure that you connect your instrument properly. Operate your centrifuge according to the operating instructions. When calibrating your centrifuge, use a stopwatch, digital thermometer and a calibrated tachometer.

Time Calibration

Using the set centrifuge parameters, set the calibration time to five minutes. Record your results using your stopwatch before repeating the exercise using a ten-minute time interval. If there is a time difference, adjust your centrifuge timing accordingly.

Revolutions Per Minute (RPM) Calibration

Fixed Angle Rotor

Set your rotor RPM to 12000 and 6000 while recording each result using a tachometer.

Swing Out Rotor

Set your rotor RPM to 4000 and 2000 while recording each result using a tachometer. If there is a deviation in RPM readings in your digital tachometer and the centrifuge, adjust it accordingly. If your centrifuge has timing and revolutions per minute problems, Biotechnical Services, Inc., is at your service for accurate and precise centrifuge calibration in San Diego.

Temperature Calibration

Fixed Angle Rotor

Using a sample of ethylene glycol, fill the tubes and place them in the sample holder. Set the temperature parameter to 5 degrees, revolutions per minute to 12000, and the time duration to 45 minutes. Record the temperature of the sample in your centrifuge using a digital thermometer. Repeat the test by adjusting the temperatures to 10 and 20 degrees and recording the temperature. If the reading in your digital thermometer is not consistent with the centrifuge setting, calibrate your centrifuge accordingly.

Swing Out Rotor

Fill the ethylene glycol sample in the centrifuge tubes and place them in a sample holder. Start by setting the temperature parameter to 5 degrees, revolutions per minute to 4000, and the timing to 45 minutes. Using a digital thermometer, record the temperature of the sample in the centrifuge. Repeat the procedure by adjusting the temperature to 10 and 20 degrees. Record the temperature readings using a thermometer. If there is a difference in temperature reading during the experiments, calibrate the temperature reading of your centrifuge to be consistent with that of the digital thermometer.


If you use your centrifuge heavily daily, always record your calibration frequency accordingly. If you want timely and precise centrifuge calibration of your centrifuge, Biotechnical Services, Inc. is at your service. We offer trusted equipment calibration with the latest technology. We are the leading experts in centrifuge calibration in San Diego.

Cleaning and Maintenance

When cleaning or disinfecting your centrifuge, use neutral agents such as isopropanol or any alcohol-based disinfectant. Ensure that you rinse the rubber seals thoroughly in your rotor chambers after using a detergent. After rinsing with water, lubricate your seals with glycerin to prevent them from being brittle. Sometimes condensation water forms in the centrifuge’s rotor chamber during freezing; use a soft and dry absorbent cloth for cleaning. Regularly clean both the bucket and the rotor to avoid contamination caused by the residue. When your centrifuge does not work according to the specifications of the parameters, label your equipment as out of calibration to prepare for servicing and repair. After repairing and servicing your centrifuge, calibrate it accordingly. At Biotechnical Services, Inc., we provide comprehensive calibration of your centrifuge(s). We provide premier and timely lab equipment calibration in San Diego.